S100B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90726A
Immunohistochemistry of paraffin-embedded Rat brain using S100B Polyclonal Antibody at dilution of 1:4700
Product Name
S100B Polyclonal Antibody
Catalog Number
RD90726A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new bomarker for mood disorders.
Immunogen Information
Immunogen
Recombinant Human S100B protein expressed by E.coli
Swissprot
P04631
Synonyms
NEFProtein S100 BProtein S100-BS 100 calcium binding protein beta chainS 100 protein beta chainS-100 protein beta chainS-100 protein subunit betaS100S100 calcium binding protein beta (neural)S100 calcium-binding protein BS100 protein beta chain
Applications
Reactivity
Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:2000-1:4700
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.