SAV1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219264A
Immunohistochemistry of paraffin-embedded Human brain tissue using SAV1 Polyclonal Antibody at dilution of 1:90(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SAV1 Polyclonal Antibody at dilution of 1:90(×200)
Product Name
SAV1 Polyclonal Antibody
Catalog Number
RD219264A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Immunogen Information
Immunogen
Fusion protein of human SAV1
Swissprot
Q9H4B6
Synonyms
1700040G09Rik45 kDa WW domain proteinhWW 45hWW45Protein salvador homolog 1salvador family WW domain containing protein 1salvador homolog 1 (Drosophila)Salvador homolog 1SalvadorDrosophilahomolog ofSAV 1SAVSAV1SAV1WW 45WW domain containin
Gene Accession
BC020537
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300, ELISA 1:5000-1:10000
Concentration
1.32 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas