SCCPDH Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD82559A
Western blot analysis of extracts of various cell lines using SCCPDH Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using SCCPDH Polyclonal Antibody at dilution of 1:1000.
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Overview

Circle
Product Name
SCCPDH Polyclonal Antibody
Catalog Number
RD82559A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human SCCPDH (NP_057086.2).
Gene ID
51097
Swissprot
Q8NBX0
Synonyms
SCCPDHCGI-49NET11
Calculated MW
47 kDa
Observed MW
45 kDa

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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