SCCPDH Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD219034A
Western blot analysis of Human fetal liver tissue PC-3 and A172 cell lysates  using SCCPDH Polyclonal Antibody at dilution of 1:1000
Western blot analysis of Human fetal liver tissue PC-3 and A172 cell lysates using SCCPDH Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human tonsil tissue  using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
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Overview

Circle
Product Name
SCCPDH Polyclonal Antibody
Catalog Number
RD219034A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Immunogen Information

Circle
Immunogen
Fusion protein of human SCCPDH
Swissprot
Q8NBX0
Synonyms
CGI 49CGI49FLJ43187Probable saccharopine dehydrogenaseSaccharopine dehydrogenaseSCCPDHSCPDH
Calculated MW
47 kDa
Observed MW
Refer to figures
Gene Accession
BC026185

Applications

Circle
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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