SCP2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD83269A
Western blot analysis of extracts of Mouse liver using SCP2 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of Mouse liver using SCP2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human liver cancer using SCP2 Polyclonal Antibody at dilution of  1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver cancer using SCP2 Polyclonal Antibody at dilution of 1:200 (40x lens).
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Overview

Circle
Product Name
SCP2 Polyclonal Antibody
Catalog Number
RD83269A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human SCP2 (NP_001007099.1).
Gene ID
6342
Swissprot
P22307
Synonyms
SCP2NLTPNSL-TPSCP-2SCP-CHISCP-XSCPX
Calculated MW
6 kDa/15 kDa/34 kDa/50 kDa/54 kDa/56 kDa/58 kDa
Observed MW
59 kDa

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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