The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
O00560
Synonyms
MDA-9MDA9Melanoma differentiation-associated protein 9Pro-TGF-alpha cytoplasmic domain-interacting protein 18Scaffold protein Pbp1SDCB1SDCBPST1SYCLSyndecan binding protein (syntenin)Syndecan binding protein 1Syndecan-binding protein 1Syntenin
Calculated MW
32 kDa
Gene Accession
BC113674
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-150, ELISA 1:2000-5000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4