This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
Immunogen Information
Immunogen
Recombinant Human Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial protien
Swissprot
P31040
Synonyms
CMD1GGDHSA_HUMANFlavoprotein subunit of complex IIFpPGL5SDH 2SDH1SDHFSuccinate dehydrogenase [ubiquinone] flavoprotein subunit
Calculated MW
72 kDa
Observed MW
72 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.