SDHB Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of PC3 and hepg2 cell, Human fetal liver tissue using SDHB Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human thyroid cancer using SDHB Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer using SDHB Polyclonal Antibody at dilution of 1:30
Product Name
SDHB Polyclonal Antibody
Catalog Number
RD79303A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Immunogen Information
Immunogen
Synthetic peptide of human SDHB
Swissprot
P21912
Synonyms
CWS2DHSBFLJ92337IpIron sulfur subunitIron sulfur subunit of complex IIIron-sulfur subunit of complex IImitochondrialPGL 4PGL4SDH 1SDHSDH1SDH2SDH2homolog ofSdhBSDHIPSuccinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrialSu
Calculated MW
32 kDa
Gene Accession
NP_002991
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas