This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human SEC14L2
Swissprot
O76054
Synonyms
Alpha tocopherol associated proteinAlpha-tocopherol-associated proteinC22orf6HGNC:10699hTAPKIAA1186KIAA1658MGC65053S14L2SEC14 like 2SEC14 like protein 2SEC14-like protein 2Sec14l2SPFSqualene transfer proteinSupernatant protein factorTAPTA
Calculated MW
46 kDa
Gene Accession
NP_001191133
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4