SEC63 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89328A
Western blot analysis of extracts of various cell lines using SEC63 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of Rat lung using SEC63 Polyclonal Antibody at 1:1000 dilution.
Product Name
SEC63 Polyclonal Antibody
Catalog Number
RD89328A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Immunogen Information
Immunogen
Recombinant fusion protein of human SEC63
Gene ID
11231
Swissprot
Q9UGP8
Synonyms
ERdj2PCLD2SEC63LDNAJC23PRO2507
Calculated MW
79kDa
Observed MW
73KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.