Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
Q15019
Synonyms
DIFF6hNEDD5KIAA0158NEDD 5NEDD5Neural precursor cell expressed developmentally down regulated 5Neural precursor cell expressed developmentally down regulated protein 5Pnutl3Protein NEDD5SEPT2septin 2
Calculated MW
41 kDa
Gene Accession
BC033559
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1000, IHC 1:25-100, ELISA 1:1000-2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4