May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation.
Immunogen Information
Immunogen
Recombinant fusion protein of human SERBP1
Gene ID
26135
Swissprot
Q8NC51
Synonyms
SERBP1CGI-55CHD3IPHABP4LPAI-RBP1PAIRBP1
Calculated MW
52kDa/105kDa
Observed MW
105kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.