SET/TAF1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87473A
Western blot analysis of extracts of various cell lines using SET/TAF1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using SET/TAF1 Polyclonal Antibody at 1:1000 dilution.
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Overview

Circle
Product Name
SET/TAF1 Polyclonal Antibody
Catalog Number
RD87473A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human SET/TAF1
Gene ID
6418
Swissprot
Q01105
Synonyms
SET2PP2AI2PP2AIGAADIPP2A2PHAPIITAF-ITAF-IBETA
Calculated MW
25kDa/34kDa
Observed MW
34kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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