SETD2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77751A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using SETD2 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SETD2 Polyclonal Antibody at dilution 1:30
Product Name
SETD2 Polyclonal Antibody
Catalog Number
RD77751A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Immunogen Information
Immunogen
Recombinant protein of human SETD2
Swissprot
Q9BYW2
Synonyms
EC 2.1.1.43FLJ16420FLJ22472FLJ23184FLJ45883HBP231HIF 1HIF-1HIF1HIP-1Histone lysine N methyltransferase SETD2Histone-lysine N-methyltransferase SETD2hSET2HSPC069Huntingtin interacting protein 1Huntingtin interacting proteinHuntingtin intera
Gene Accession
BC117162
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas