SETMAR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252907A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SETMAR Polyclonal Antibody at dilution of 1:100(×200)
Product Name
SETMAR Polyclonal Antibody
Catalog Number
RD252907A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human SETMAR
Swissprot
Q53H47
Synonyms
Histone lysine N methyltransferaseHistone lysine N methyltransferase SETMARHsmar 1Hsmar1Mariner transposase Hsmar1MetnaseSET domain and mariner transposase fusionSET domain and mariner transposase fusion geneSET domain and mariner transposase fusi
Gene Accession
BC011635
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.8 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas