SF3B2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD83555A
Immunohistochemistry of paraffin-embedded Rat heart using SF3B2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human lung cancer using SF3B2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse Intestine using SF3B2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of A-549 cells using SF3B2 Polyclonal Antibody
Product Name
SF3B2 Polyclonal Antibody
Catalog Number
RD83555A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
Immunogen Information
Immunogen
Recombinant fusion protein of human SF3B2 (NP_006833.2).
Gene ID
10992
Swissprot
Q13435
Synonyms
SF3B2Cus1SAP145SF3B145SF3b1SF3b150
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas