SH-PTP1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western Blot analysis of A375 and A431 cell using SH-PTP1 Polyclonal Antibody at dilution of 1:500
Western Blot analysis of A375 and A431 cell using SH-PTP1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
Immunohistochemistry of paraffin-embedded Human colon cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
Immunohistochemistry of paraffin-embedded Human liver cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
Immunohistochemistry of paraffin-embedded Human liver cancer using SH-PTP1 Polyclonal Antibody at dilution of 1:35
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

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Product Name
SH-PTP1 Polyclonal Antibody
Catalog Number
RD75345A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported.

Immunogen Information

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Immunogen
Recombinant protein of human PTPN6
Swissprot
P29350
Synonyms
70Z-SHPEC 3.1.3.48HCPHCPHHematopoietic cell phosphataseHematopoietic cell protein tyrosine phosphataseHematopoietic cell protein-tyrosine phosphataseHPTP1CProtein tyrosine phosphatase 1CProtein tyrosine phosphatase non receptor type 6Protein tyr
Calculated MW
68 kDa
Gene Accession
BC002523

Applications

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Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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