SH3PXD2A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot analysis of extracts of HeLa cells using SH3PXD2A Polyclonal Antibody
Immunofluorescence analysis of L929 cells using SH3PXD2A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
SH3PXD2A Polyclonal Antibody
Catalog Number
RD89984A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs, NADPH oxidases (NOXs and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
Immunogen Information
Immunogen
Recombinant fusion protein of human SH3PXD2A
Gene ID
9644
Swissprot
Q5TCZ1
Synonyms
SH3PXD2AFISHSH3MD1TKS5
Calculated MW
71kDa/99kDa
Observed MW
110kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.