SIGLEC5 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77930A
Western Blot analysis of Mouse liver tissue using SIGLEC5 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human gastic cancer using SIGLEC5 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human colon cancer using SIGLEC5 Polyclonal Antibody at dilution of 1:30
Product Name
SIGLEC5 Polyclonal Antibody
Catalog Number
RD77930A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
Immunogen Information
Immunogen
Recombinant protein of human SIGLEC5
Swissprot
O15389
Synonyms
CD170CD170 antigenCD33 antigen-like 2CD33L2mSiglec-FOB-binding protein 2OB-BP2OBBP2Obesity-binding protein 2Sialic acid binding Ig-like lectin 5Sialic acid binding immunoglobulin-like lectin 5Sialic acid-binding Ig-like lectin 5Sialic acid-bin
Calculated MW
61 kDa
Gene Accession
BC029896
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas