SIGLEC8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80424A
Western blot analysis of extracts of various cell lines using SIGLEC8 Polyclonal Antibody at dilution of 1:1000.
Product Name
SIGLEC8 Polyclonal Antibody
Catalog Number
RD80424A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein .
Immunogen Information
Immunogen
Recombinant fusion protein of human SIGLEC8 (NP_055257.2).
Gene ID
27181
Swissprot
Q9NYZ4
Synonyms
SIGLEC8SAF2SIGLEC-8SIGLEC8L
Calculated MW
44 kDa/46 kDa/54 kDa
Observed MW
60 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas