SIN3B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87290A
Western blot analysis of extracts of various cell lines using SIN3B Polyclonal Antibody at 1:1000 dilution.
Variation
Quantity
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Overview
Product Name
SIN3B Polyclonal Antibody
Catalog Number
RD87290A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Immunogen Information
Immunogen
Recombinant fusion protein of human SIN3B
Gene ID
23309
Swissprot
O75182
Synonyms
SIN3B
Calculated MW
36kDa
Observed MW
36kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas