This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse SIRT7
Swissprot
Q9NRC8,Q8BKJ9
Synonyms
NAD dependent deacetylase sirtuin 7NAD dependent protein deacetylase sirtuin 7NAD-dependent protein deacetylase sirtuin-7Regulatory protein SIR2 homolog 7Silent mating type information regulation 2 homologSilent mating type information regulation 2 S
Applications
Reactivity
Human
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:400
Concentration
190 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4