This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia.
Immunogen Information
Immunogen
Recombinant protein of human SLC12A4
Swissprot
Q9UP95
Synonyms
Electroneutral potassium chloride cotransporter 1Electroneutral potassium-chloride cotransporter 1Erythroid K Cl cotransporter 1Erythroid K-Cl cotransporter 1FLJ40489hKCC 1hKCC1KCC 1KCC1Potassium transport proteinPotassium/chloride cotransporter
Gene Accession
BC021193
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4