Mediates the electrogenic exchange of Ca(2+ against Na(+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+ levels and Ca(2+-dependent cellular processes. Contributes to cellular Ca(2+ homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+ levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+ and Na(+ excretion.
Immunogen Information
Immunogen
Recombinant fusion protein of human SLC8A2
Gene ID
6543
Swissprot
Q9UPR5
Synonyms
SLC8A2NCX2
Calculated MW
42kDa
Observed MW
50-55kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.