This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human SLC9A3R2
Swissprot
Q15599
Synonyms
E3KARPHGNC:11076Isoform 3 regulator 2Isoform 3 regulatory factor 2MGC104639Na(+)/H(+) exchange regulatory cofactor NHE RF2Na(+)/H(+) exchange regulatory cofactor NHE-RF2NHE3 kinase A regulatory proteinNHE3 kinase A regulatory protein E3KARPNHE3 r
Gene Accession
NP_001123484.1
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4