Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).
Immunogen Information
Immunogen
Fusion protein of human SLITRK5
Swissprot
O94991
Synonyms
bA364G4.2KIAA0918Leucine rich repeat containing 11Leucine rich repeat containing protein 11LRRC 11LRRC11SLIT and NTRK like family member 5SLIT and NTRK like protein 5Slit and trk like gene 5SLITRK 5