The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated witHuman, Mousealignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human SMARCB1
Swissprot
Q12824
Synonyms
BAF47BRG1-associated factor 47hSNF5INI1Integrase interactor 1 proteinMalignant rhabdoid tumor suppressorRDTRTPS1Sfh1pSMARCB1SNF5 homologSNF5SNF5L1Snr1Sucrose nonfermenting yeast homolog like 1SWI/SNF complex component SNF5SWI/SNF-related m
Calculated MW
44 kDa
Gene Accession
BC117114
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4