SNCA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76715A
Immunohistochemistry of paraffin-embedded Human brain tissue using SNCA Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SNCA Polyclonal Antibody at dilution 1:30
Product Name
SNCA Polyclonal Antibody
Catalog Number
RD76715A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human SNCA
Swissprot
P37840
Synonyms
Alpha synucleinAlpha-synucleinAlpha-synucleinisoform NACP140alphaSYNMGC105443MGC110988MGC127560MGC64356NACPNon A beta component of AD amyloidNon A4 component of amyloidNon A4 component of amyloid precursorNon-A beta component of AD amyloidNo
Gene Accession
NP_000336
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas