SOCS1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70446A
Immunohistochemistry analysis of paraffin-embedded mouse spleen using SOCS1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse brain using SOCS1 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat kidney using SOCS1 Polyclonal Antibody at dilution of 1:300.
Product Name
SOCS1 Polyclonal Antibody
Catalog Number
RD70446A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse SOCS1
Swissprot
O35716,Q9QX78
Synonyms
CISH 1CISH1Cytokine inducible SH2 protein 1JABJAK binding proteinJAK-binding proteinJanus kinase binding proteinSOCS 1SOCS-1Socs1SOCS1SSI 1SSI-1SSI1STAT induced STAT inhibitor 1STAT-induced STAT inhibitor 1Suppressor of cytokine signaling
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:200-1:800
Concentration
0.89 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.