SOCS3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80136A
Western blot analysis of extracts of various cell lines using SOCS3 Polyclonal Antibody at dilution of 1:3000.
Product Name
SOCS3 Polyclonal Antibody
Catalog Number
RD80136A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Immunogen Information
Immunogen
A synthetic peptide of human SOCS3 (NP_003946.3).
Gene ID
9021
Swissprot
O14543
Synonyms
SOCS3ATOD4CIS3Cish3SOCS-3SSI-3SSI3
Calculated MW
24 kDa
Observed MW
33 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.