SOCS7 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76426A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using SOCS7 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using SOCS7 Polyclonal Antibody at dilution 1:30
Variation
Quantity
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Overview
Product Name
SOCS7 Polyclonal Antibody
Catalog Number
RD76426A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.
Immunogen Information
Immunogen
Synthetic peptide of human SOCS7
Swissprot
O14512
Synonyms
Ash and phospholipase C gamma-binding proteinNAP 4NAP 4 FragmentNAP-4NAP4NckNck Ash and phospholipase C binding proteinNck Ash and phospholipase C gamma binding proteinNck associated protein 4Nck-associated protein 4NCKAP4SH2 domain containing
Gene Accession
NP_055413
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas