Sorbitol Dehydrogenase Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90279A
Western blot analysis of extracts of various cell lines using Sorbitol Dehydrogenase Polyclonal Antibody at 1:1000 dilution.
Product Name
Sorbitol Dehydrogenase Polyclonal Antibody
Catalog Number
RD90279A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Immunogen Information
Immunogen
Recombinant fusion protein of human Sorbitol Dehydrogenase
Gene ID
6652
Swissprot
Q00796
Synonyms
SORDHEL-S-95nSORD1
Calculated MW
44kDa
Observed MW
12KDa/25KDa/45-60KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas