SORD Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253170A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SORD Polyclonal Antibody at dilution of 1:45(×200)
Product Name
SORD Polyclonal Antibody
Catalog Number
RD253170A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Immunogen Information
Immunogen
Fusion protein of human SORD
Swissprot
Q00796
Synonyms
DHSOL iditol 2 dehydrogenaseL-iditol 2-dehydrogenaseOTTHUMP00000161939SDHSorbitol dehydrogenase 1Sorbitol dehydrogenaseSORD 1SORDSORD1
Gene Accession
BC021085
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100, ELISA 1:5000-1:10000
Concentration
0.78 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas