The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse SOX9
Swissprot
Q04887
Synonyms
campomelic dysplasia autosomal sex reversalCMD 1CMD1CMPD 1CMPD1SOX 9Sox9SOX9SRA 1SRA1SRXX2SRXY10SRY (sex determining region Y) box 9 (campomelic dysplasia autosomalSRY (sex determining region Y) box 9SRY (sex determining region Y)-box 9SRY
Calculated MW
56 kDa
Observed MW
56 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4