SPCS2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot analysis of K-562 cell Human placenta tissue Mouse adrenal gland tissue HT-29 cell NIH/3T3 cell Rat lung tissue using SPCS2 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SPCS2 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using SPCS2 Polyclonal Antibody at dilution of 1:40(×200)
Product Name
SPCS2 Polyclonal Antibody
Catalog Number
RD218383A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
SPCS2 (signal peptidase complex subunit 2), also known as SPC25 or microsomal signal peptidase 25 kDa subunit, is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Immunogen Information
Immunogen
Fusion protein of human SPCS2
Swissprot
Q15005
Synonyms
Microsomal signal peptidase 25 kDa subunitSignal peptidase complex subunit 2Signal peptidase complex subunit 2 homolog (S. cerevisiae)SPase 25 kDa subunitSPCS2SPCS2
Calculated MW
25 kDa
Observed MW
Refer to figures
Gene Accession
BC082231
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas