SPG20 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD88893A
Western blot analysis of extracts of various cell lines using SPG20 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using SPG20 Polyclonal Antibody at 1:1000 dilution.
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Overview

Circle
Product Name
SPG20 Polyclonal Antibody
Catalog Number
RD88893A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human SPG20
Gene ID
23111
Swissprot
Q8N0X7
Synonyms
SPARTINTAHCCP1SPG20spartin
Observed MW
104kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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