SPHK2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75589A
Western Blot analysis of Mouse brain and liver tissue using SPHK2 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human thyroid cancer using SPHK2 Polyclonal Antibody at dilution of 1:60
Product Name
SPHK2 Polyclonal Antibody
Catalog Number
RD75589A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Immunogen
Recombinant protein of human SPHK2
Swissprot
Q9NRA0
Synonyms
SK 2Sphingosine kinase 2Sphingosine kinase type 2SPHK2SPHK2SPK 2
Calculated MW
69 kDa
Gene Accession
BC006161
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas