SPRTN Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using SPRTN Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using SPRTN Polyclonal Antibody at dilution of 1:65(×200)
Product Name
SPRTN Polyclonal Antibody
Catalog Number
RD252495A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.
Immunogen Information
Immunogen
Fusion protein of human SPRTN
Swissprot
Q9H040
Synonyms
C1orf124CA124Chromosome 1 open reading frame 124DDDL1880dJ876B10.3PRO4323RP5-876B10.3SpartanSprT-like domain at the N terminusSprT-like N-terminal domainZinc finger RAD18 domain-containing protein C1orf124
Gene Accession
BC015740
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas