This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
Q9C004
Synonyms
Protein sprouty homolog 4Sprouty homolog 4sprouty homolog 4 (Drosophila)SPRY 4Spry-4Spry4SPY4