SPSB1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87214A
Western blot analysis of extracts of mouse heart using SPSB1 Polyclonal Antibody at 1:1000 dilution.
Product Name
SPSB1 Polyclonal Antibody
Catalog Number
RD87214A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Negatively regulates nitric oxide (NO production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2. Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5.
Immunogen Information
Immunogen
Recombinant fusion protein of human SPSB1
Gene ID
80176
Swissprot
Q96BD6
Synonyms
SPSB1SSB-1SSB1
Calculated MW
236kDa/266kDa/278kDa
Observed MW
280kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.