Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation.
Immunogen Information
Immunogen
Synthetic peptide of human SPTAN1
Swissprot
Q13813
Synonyms
(ALPHA)II-SPECTRINAlpha II SpectrinAlpha-II spectrinbrainEIEE5FLJ17738FLJ44613Fodrin alpha chainFodrinalphaNEASNon erythrocytic spectrin alphanon-erythroid alpha chainSPECASpectrin alpha chainSpectrin alpha chain brainSpectrin alpha non er
Gene Accession
NP_003118
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4