SSCA1/SerpinB3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89675A
Western blot analysis of 293T using SSCA1/SerpinB3 Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of A431 cells using SSCA1/SerpinB3 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HepG2 cells using SSCA1/SerpinB3 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Variation
Quantity
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Overview
Product Name
SSCA1/SerpinB3 Polyclonal Antibody
Catalog Number
RD89675A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Immunogen Information
Immunogen
Recombinant fusion protein of human SSCA1/SerpinB3
Gene ID
6317
Swissprot
P29508
Synonyms
SERPINB3HsT1196SCCSCCA-1SCCA-PDSCCA1SSCA1T4-Aserpin B3
Calculated MW
211kDa/212kDa
Observed MW
150kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas