The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors.
Immunogen Information
Immunogen
Recombinant protein of human ST14
Swissprot
Q9Y5Y6
Synonyms
EpithinHAIMatriptaseMembrane type serine protease 1Membrane type serine proteaseMembrane-type serine protease 1MT SP1MT-SP1MTSP 1MTSP1ProstaminPRSS 14PRSS14Serine protease 14Serine protease TADG 15Serine protease TADG-15Serine protease TAD
Gene Accession
BC030532
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4