Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.
Immunogen Information
Immunogen
Synthetic peptide of human STARD5
Swissprot
Q9NSY2
Synonyms
MGC10327StAR related lipid transfer protein 5StAR-related lipid transfer (START) domain containing 5StARD5START domain containing 5START domain containing protein 5
Calculated MW
24 kDa
Gene Accession
NP_871629
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:40-1:150
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4