The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Stat1
Swissprot
P42224,P42225,
Synonyms
Signal transducer and activator of transcription 1 91kDCANDF7DKFZp686B04100IMD31AIMD31BIMD31CISGF 3ISGF-3OTTHUMP00000163552OTTHUMP00000165046OTTHUMP00000165047OTTHUMP00000205845Signal transducer and activator of transcription 1 91kDaSignal tr
Calculated MW
87 kDa
Observed MW
87 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.86 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4