STAT2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78902A
Western Blot analysis of PC3 cell using STAT2 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human gastic cancer using STAT2 Polyclonal Antibody at dilution of 1:60
Product Name
STAT2 Polyclonal Antibody
Catalog Number
RD78902A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
Immunogen Information
Immunogen
Synthetic peptide of human STAT2
Swissprot
P52630
Synonyms
Homo sapiens interferon alpha induced transcriptional activatorinterferon alpha induced transcriptional activatorISGF 3ISGF3MGC59816P113signal transducer and activator of transcription 2 113kDSignal transducer and activator of transcription 2STAT1
Calculated MW
98 kDa
Gene Accession
NP_005410
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas