This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen Information
Immunogen
Synthetic peptide of human STEAP2
Swissprot
Q8NFT2
Synonyms
4921538B17RikAI930049IPCA 1IPCA1Metalloreductase STEAP2PCANAP 1PCANAP1Prostate cancer associated protein 1Prostate cancer-associated protein 1Protein up regulated in metastatic prostate cancerProtein upregulated in metastatic prostate cancerPU