STK4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD84873A
Western blot analysis of extracts of various cells using STK4 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human breast cancer using STK4 Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
STK4 Polyclonal Antibody
Catalog Number
RD84873A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Immunogen Information
Immunogen
Recombinant fusion protein of human STK4 (NP_006273.1).
Gene ID
6789
Swissprot
Q13043
Synonyms
KRS2MST1YSK3STK4
Calculated MW
52 kDa/55 kDa
Observed MW
56 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas