STK40 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77802A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using STK40 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using STK40 Polyclonal Antibody at dilution 1:40
Product Name
STK40 Polyclonal Antibody
Catalog Number
RD77802A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.
Immunogen Information
Immunogen
Recombinant protein of human STK40
Swissprot
Q8N2I9
Synonyms
2310004N11RikMGC4796OTTHUMP00000009948OTTHUMP00000009951RP11-268J15.4Ser/Thr like kinaseSerine/threonine kinase 40Serine/threonine protein kinase 40SgK495SHIKSINK homologous serine/threonine protein kinaseSINK-homologous inhibitory kinaseSTK 4
Gene Accession
BC008344
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.