TAB3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75958A
Western Blot analysis of 293T, Raw264.7, NIH/3T3, K562 and Jurkat cell using TAB3 Polyclonal Antibody at dilution of 1:800
Product Name
TAB3 Polyclonal Antibody
Catalog Number
RD75958A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.
Immunogen Information
Immunogen
Recombinant protein of human TAB3
Swissprot
Q8N5C8
Synonyms
MAP3K7IP 3Mitogen-activated protein kinase kinase kinase 7-interacting protein 3NAP1NF-kappa-B-activating protein 1NFkB activating protein 1TAB-3Tab3TAB3TAK1 binding protein 3TAK1-binding protein 3TGF-beta-activated kinase 1 and MAP3K7-binding p
Calculated MW
79 kDa
Gene Accession
BC032526
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.